43 paediatric and adult CF centres form the Trials Accelerator network. Our network of centres works collaboratively to help people with CF from all over the UK access a range of new therapies being developed for CF through taking part in clinical trials. You can read more about our centres and who they are here.
Download our Sponsors brochure
Our Sponsors brochure outlines how the Trials Accelerator can support Sponsors who have a CF therapy portfolio.
Download the brochure
‘Patient & Public Involvement’ (PPI) is regarded as a highly important component of the UK regulatory process, with the UK Health Research Authority (HRA) strongly encouraging all Sponsors to engage with PPI during trial design. It is now widely acknowledged that the inclusion of PPI at all stages of the trials process leads to better recruitment and retention rates.
PPI should be an active and collaborative opportunity for Sponsors and the CF community that allows the community to act as advisers and partners. The Trials Accelerator has an established group of CF representatives (people with CF, and parents of children with CF) ready to share their lived experience to support Sponsors with trial design and delivery.
This PPI group can benefit Sponsors by offering:
- Access to an engaged and diverse representation of the CF community
- Focus group discussions via remote technology
- One-to-one interviews to access a specific knowledge base
- Protocol reviews by trained CF representatives
- Review of design and content of Patient Information Sheets and Consent Forms
- Lay trial summaries and lay result summaries
Maximum benefit can be achieved by initiating PPI at the earliest possible stage, but it does not exclude involving CF representatives in the latter stages of trials even when there has been no PPI previously.
Please review the Trials Accelerator Sponsors Brochure or contact the Trials Accelerator Involvement Manager (email@example.com) for more information.