A trial investigating the effect of a sinus rinse in people with CF

Details

Therapeutic category
Anti-Infective
Trial status
Recruitment on hold - COVID-19

Full title

A pilot study investigating the effects of manuka honey sinus rinse on sino-nasal outcome test scores in people with CF.

People with with CF often have bacterial infection in their air ways. There is great interest in the different types of bacteria found within these infections. This clinical trial looks at whether a novel sinus rinse device (that incorporates manuka honey) could help clear infection or reduce the amount and/or types of bacteria found within the upper airway. This study assesses the changes in the Sino-Nasal Outcome Test (SNOT-22) scores along with any changes in quality of life, before and after the use of a sinus rinse device for 30 days. In addition to this, the amount and types of bacteria found in nasal swabs, the sinus rinse solution, and sputum samples, before and after using the sinus rinse device will be investigated. Sputum samples will also be monitored for changes in composition before and after using the sinus rinse.


Trial Reference Number
136232
Trial type
Non-medication
Recruitment target
0
Last edited date
29/09/2020
CF sponsor type
Academic

Who can take part?

Top inclusion criteria
  • 18 years or older
  • Chronic symptoms of rhinosinusitis according to the criteria of the European Position Paper on Rhinosinusitis
  • Scores greater or equal to 7 on their SNOT-22 questionnaire.
Top exclusion criteria
  • Previously tested positive for the bacteria Mycobacterium tuberculosis.
  • Currently using a nasal rinse protocol
  • Known allergy to bee products

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