HOPE-1

Details

Therapeutic approach
Mucociliary Clearance
Trial status
Closed with results Participating Centres
Trials Tracker ID
TT001791
Last updated
02/10/2017

Full title

A Randomized, Double-blind, Placebo-controlled Phase II Study to Evaluate the Efficacy and Safety of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis (HOPE-1 Study: Hydration for Optimal Pulmonary Effectiveness)

Study details

Evaluation of potential mucus clearing treatment for all patients with CF regardless of mutation


Phase
Phase 2
Recruitment target
80
CF sponsor
Spyryx Biosciences, Inc.
CF sponsor type
Commercial

Who can take part?

Age range
18 years and older
Including people

Age 18 years or older
Stable CF Lung Disease

Excluding people

Significant unstable co-morbidities within 28 days of screening.
Has received an investigational drug within 28 days of screening

Get in touch

Your donation will make a difference:

Select amount
Select amount

CF centres running this trial

Closed

Belfast City Hospital (Adults)

CTAP centre
NHS Trust
Belfast Health & Social Care Trust
Address
Lisburn Road
BT9 7AB
Recruitment starts
Recruitment ends
Local site investigator
Damian Downey
Trial Coordinators
Catherine McNeill
Closed

Birmingham Heartlands Hospital (Adults)

CTAP centre
NHS Trust
University Hospitals Birmingham NHS Foundation Trust
Address
Bordesley Green
B9 5SS
Recruitment starts
Recruitment ends
Local site investigator
Edward Nash
Trial Coordinators
Aoife Neal
Closed

Bristol Royal Infirmary (Adults)

CTAP centre
NHS Trust
University Hospitals Bristol NHS Foundation Trust
Address
Marlborough Street
BS2 8HW
Recruitment starts
Recruitment ends
Local site investigator
Nicholas Bell
Trial Coordinators
Sally Coplowe
Closed

Cambridge Royal Papworth Hospital (Adults)

CTAP centre
NHS Trust
Royal Papworth Hospital NHS Foundation Trust
Address
Papworth Road
CB2 0AY
Trial Coordinators
Deepa George
Victoria Christenssen
Closed

Edinburgh - Western General Hospital (Adults)

CTAP centre
NHS Trust
NHS Lothian
Address
Crewe Road South
EH4 2XU
Recruitment ends
Trial Coordinators
Ellyse Kilarski
Closed

Glasgow - Queen Elizabeth University Hospital

CTAP centre
NHS Trust
NHS Greater Glasgow & Clyde
Address
1345 Govan Road
G51 4TF
Recruitment starts
Recruitment ends
Local site investigator
Gordon MacGregor
Trial Coordinators
Annie Husband
Closed

Liverpool Heart and Chest Hospital

NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust
Address
Thomas Drive
Liverpool
L14 3PE
Recruitment starts
Local site investigator
Martin Ledson
Closed

Manchester (Adults) - Wythenshawe Hospital

CTAP centre
NHS Trust
Manchester University NHS Foundation Trust
Address
Wythenshawe Hospital
South Moor Road
M23 9LT
Local site investigator
Alex Horsley
Trial Coordinators
Sarah Sampson
Closed

Nottingham City Hospital (Adults)

CTAP centre
NHS Trust
Nottingham University Hospitals NHS Foundation Trust
Address
City Hospital, Wolfson Cystic Fibrosis Centre
Hucknall Road
NG5 1PB
Recruitment starts
Local site investigator
Helen Barr
Trial Coordinators
Fozia Naushahi
Closed

Royal Brompton Hospital (London)

CTAP centre
NHS Trust
Guy's and St Thomas' NHS Foundation Trust
Address
Royal Brompton Hospital
Sydney Street
SW3 6NP
Recruitment starts
Local site investigator
Nicholas Simmonds
Trial Coordinators
Sophie Pinnell
Closed

Royal Devon & Exeter Hospital

CTAP centre
NHS Trust
The Royal Devon & Exeter NHS Foundation Trust
Address
Barrack Road
EX2 5DW
Recruitment starts
Recruitment ends
Local site investigator
Nick Withers
Trial Coordinators
Sophie Whiteley
Closed

St Bartholomew's Hospital (London) - Adults

CTAP centre
NHS Trust
Barts Health NHS Trust
Address
West Smithfield
EC1A 7BE
Recruitment starts
Recruitment ends
Local site investigator
Nadia Shafi
Trial Coordinators
Sandra Pereira
Closed

St James's University Hospital - Leeds (Adults)

CTAP centre
NHS Trust
The Leeds Teaching Hospitals NHS Trust
Address
St James's University Hospital
Beckett Street
LS9 7TF
Recruitment starts
Local site investigator
Daniel Peckham
Trial Coordinators
Helen Chadwick