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Cystic Fibrosis Trust

Pseudomonas in our sights

Researchers post progress in understanding, detecting and treating Pseudomonas infections.

An international team of researchers funded by the Cystic Fibrosis Trust is exploring potential new ways of identifying Pseudomonas infection, one of the deadliest bugs facing people with cystic fibrosis, which could help earlier treatment and limit the resulting lung damage.

Reporting back at the end of the first of its three years, the Strategic Research Centre (SRC) led by Professor Jane Davies has also explored how the behaviour of the bacteria could offer an early warning before an exacerbation (flare-up), and begun testing new ways to disperse the bacterial biofilm, a glue-like build up that is one of the most damaging aspects of a Pseudomonal infection.

Pseudomonas affects almost two-thirds of people with cystic fibrosis by the time they are young adults, and the excessive inflammation caused by infections can cause severe lung damage.

Professor Davies said: "

The SRC funding has allowed us to attract bright, energetic scientists to work together on this major problem, and grow into the CF researchers of the future. We are all very grateful for the fundraising efforts of the wider CF community."

The SRC has also produced a review of the field, which has been accepted for publication, and has given several early-career researchers the opportunity to enter the field of CF research.

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11-year-old Pippa Miles used her love of sci-fi to write this amazing story  to help overcome her dislike of needles, after some bad experiences with IVs while being treated for Pseudomonas.