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Cystic Fibrosis Trust

What causes cystic fibrosis?

People have cystic fibrosis (CF) because a faulty gene is passed from each parent to the child.

CF can't be caught or developed. If you are not born with CF you will never have it, but you could be a CF gene carrier. However, some people with CF are not diagnosed until later in life.


Diagram explaining inheritance of CF gene


One in 25 people carry the CF gene. For someone to be born with CF, both parents must carry the faulty gene. If both parents have the gene, there is a 25% chance the child will have CF. If both parents carry the gene there is also a 50% chance of the child being a gene carrier but not having CF and a 25% chance they will not have the CF gene.


The Trust is committed to funding and supporting cutting-edge research to find new and better treatments for cystic fibrosis. Take a look at some of that work and the progress that is being made.

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What is cystic fibrosis?

Find out more about cystic fibrosis, its diagnosis and how it is treated, as well as useful links to our publications and other organisations who can help.

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