TRAJECTORY: A study of the long-term impact of Kaftrio in people with cystic fibrosis

Details

CTAP badge
Therapeutic approach
Observational
Trial status
Recruitment complete Participating Centres
Trials Tracker ID
TT007421
Last updated
13/07/2022

Full title

A study of the long-term impact of Kaftrio treatment in people with cystic fibrosis in the real world

Study details

The purpose of this observational study is to collect information on the clinical characteristics (such as CFTR genotype and disease severity), treatment requirements (such as hospital visits and use of antibiotics), and quality of life of people with cystic fibrosis who are taking Kaftrio prescribed by their doctor as part of their routine care.



This is an observational study. Participants do not have to complete any additional study procedures or attend study visits, but will be asked to give informed consent for their data to be used in the study.



The data collected in this study is information that is already documented in the patient's medical records while receiving usual care as directed by their doctor and other healthcare providers.


Phase
Not applicable
Length of participation
60 months (5 years)
Recruitment target
55
CF sponsor
Vertex
CF sponsor type
Commercial

Who can take part?

Age range
Aged 6 years and older
Including people

People with CF who are aged 6 years and older and eligible for treatment with Kaftrio.

Excluding people

People with CF currently participating in interventional studies or managed access programmes will not be eligible for this study.

Get in touch

CF centres running this trial

Closed

Bristol Royal Infirmary (Adults)

CTAP centre
NHS Trust
University Hospitals Bristol NHS Foundation Trust
Address
Marlborough Street
BS2 8HW
Local site investigator
Dr Nicholas Bell
Trial Coordinators
Sally Coplowe
Closed

Cardiff - University Hospital Llandough (Adults)

CTAP centre
NHS Trust
Cardiff and Vale University Health Board
Address
Penland Road
Llandough
CF64 2XX
Local site investigator
Dr Jamie Duckers
Trial Coordinators
Catherine Joyce
Closed

Glasgow - Queen Elizabeth University Hospital

CTAP centre
NHS Trust
NHS Greater Glasgow & Clyde
Address
1345 Govan Road
G51 4TF
Local site investigator
Dr Gordon MacGregor
Trial Coordinators
Annie Husband
Closed

Leicester Royal Infirmary (Paediatrics)

CTAP affiliate centre
NHS Trust
University Hospitals of Leicester NHS Trust
Address
Infirmary Square
LE1 5WW
Local site investigator
Dr Imad Ahmed
Closed

Nottingham City Hospital (Adults)

CTAP centre
NHS Trust
Nottingham University Hospitals NHS Foundation Trust
Address
City Hospital, Wolfson Cystic Fibrosis Centre
Hucknall Road
NG5 1PB
Local site investigator
Dr Helen Barr
Trial Coordinators
Fozia Naushahi
Christina Francis
Closed

St Bartholomew's Hospital (London) - Adults

CTAP centre
NHS Trust
Barts Health NHS Trust
Address
West Smithfield
EC1A 7BE
Local site investigator
Dr Danie Watson