Cystic Fibrosis Trust announces £1.4m co-funding for two new Strategic Research Centres
Cystic Fibrosis Trust, together with the Cystic Fibrosis Foundation, is today announcing the £1.4m funding of two new Strategic Research Centres (SRCs) to target key research priorities identified by people with CF.
Cystic fibrosis is a lifelong, life limiting condition with a median age of death of just 38 years old. Despite recent treatment breakthroughs, CF remains a cruel condition with no cure.
SRCs are virtual centres of excellence bringing together researchers from within and outside of the field of CF, supporting scientists and other specialists around the world to work together to address specific issues arising from cystic fibrosis. Since 2013, Cystic Fibrosis Trust has funded 25 SRCs, assembling over 140 scientists and specialists from over 15 countries around the world – tackling everything from joint pain to gene editing.
We’re so proud to be funding the research that matters most to people with CF. We hope that these two new centres, funded jointly with the Cystic Fibrosis Foundation, will help find new treatments, and stop CF damaging and shortening lives.
Dr Lucy Allen, Director of Research and Healthcare data at Cystic Fibrosis Trust
The first new SRC, Pulmonary Magnetic Resonance Imaging for Cystic Fibrosis (MAGNIFY study), will be run by Professor Jim Wild at the University of Sheffield, and will investigate whether an exciting new type of magnetic resonance imaging (MRI) could be used to track subtle changes in lung health over time. This could be used to manage the day-to-day health of people with CF, as well as checking the effectiveness of new treatments in clinical trials.
MRI offers many advantages over current methods of assessing lung disease and is especially well suited to the new era of CF medicine – for those able to benefit from current life-changing medicines and those who are not. Working with a team of clinicians, physicists, scientists, mathematicians and people with CF, we aim to make lung MRI a normal part of managing CF and reviewing new treatments in the future
Professor Jim Wild
The second, Restoring the Fizz: Pharmacological repair of bicarbonate transport in cystic fibrosis, will be run by Dr Paola Vergani at University College London, and aims to better understand how the flow of bicarbonate in different organs is affected by CF. Researchers hope the SRC could inform future treatment choices and help us understand more about CF disease outside of the lungs.
We’re delighted to receive this SRC funding. It will allow a diverse group of CF experts around Europe to work together more easily and make faster progress. We hope that our lab-based studies will generate ideas on how to treat CF in the future, with medicines more suited to individuals based on the form of CF they have and the severity of different symptoms.
Dr Paola Vergani
Both SRCs will start in September 2023 and will run for over four and three years respectively.
Since 1964, we've supported people with cystic fibrosis to live longer, healthier lives -and we won’t stop until everyone can live without limits imposed by CF.
Despite improvements in treatments, cystic fibrosis is still a cruel condition without a cure and there is still so much more to do to stop CF damaging and shortening lives.
We need your help to fund more SRCs, speed up progress, and make sure everyone with CF can live a life unlimited.