PANORAMIC

Details

Therapeutic approach
Anti-Infective
Trial status
Open to recruitment
Trials Tracker ID
TT007061
Last updated
19/11/2021

Full title

PANORAMIC: A study investigating new antiviral medications for early treatment of COVID-19

Study details

PANORAMIC is a UK-wide clinical study which is looking to find out which people aged over 50 years old, or 18-49 years old and clinically vulnerable, respond to new antiviral treatments for COVID-19, reducing the need for hospital admission and improving speed of recovery.



The study is open to people who have tested positive for COVID-19 through a PCR or Lateral Flow test and who have ongoing symptoms of COVID-19, regardless of vaccination status.



The first treatment being investigated is the antiviral treatment called Molnupiravir. Other antiviral treatments may be included at later stages of the study. Participants will be randomly assigned to one of two groups; one group receives the usual NHS standard of care and the other group receives the antiviral treatment in addition to usual care. The study will look at whether the antiviral treatment is effective at preventing more severe symptoms of COVID-19 and hospitalisation.



You can participate in your own home from anywhere in the UK, as no face-to-face visits are required. Follow-up will involve answering questions each day for 1 month and after 3 and 6 months. This will be done online and/or by telephone calls with the study team.



You can sign up to the study via the PANORAMIC website (www.panoramictrial.org), participating GP practices and other NHS sites across the UK.


Phase
Phase 3
Length of participation
6 months
Recruitment target
10600
CF sponsor
University of Oxford
CF sponsor type
Academic

Who can take part?

Age range
18+
Including people

A positive PCR or Lateral Flow test
Ongoing COVID-19 symptoms
Aged 50 years and older OR aged 18-49 years with any known underlying chronic health condition which makes you clinically vulnerable (includes cystic fibrosis)

Excluding people

Currently admitted to hospital as an inpatient for any reason
Previous participation in the PANORAMIC study
Currently participating in a clinical trial of a therapeutic agent for acute COVID-19

Remote participation
Remote participation is possible for this trial
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