CF-TRACKER
Details
- Therapeutic approach
- Observational
- Trial status
- Open to recruitment Participating Centres
- Trials Tracker ID
- TT014530
- Last updated
- 18/03/2025
The CF-Tracker study: Identifying the causes and risk factors of pulmonary exacerbations in cystic fibrosis
Study detailsThe Tracker study is a mostly home-based study to understand the causes of exacerbations in people with cystic fibrosis (CF). We will recruit people with CF when they are well and they will track their symptoms, lung function and viral infections by sending back samples from home. These samples and information will help us build up a detailed picture of what makes one person more likely to have an exacerbation rather than recover, and also what the triggers are that make this more likely. For example, we are looking in detail at viral infections, as well as sputum bacterial infections, pollution and other aspects of CF health. If we know what causes exacerbations, and who is most at risk, we can use this to help prevent exacerbations in the first place. This would help people with CF lead healthier lives, and avoid the disruption and costs of being unwell.
You can find more information about participating in this study here.
The CF-Tracker study is part of the PULSE-CF Innovation Hub, co-funded by Cystic Fibrosis Trust and LifeArc. You can read more about PULSE-CF and the Translational Innovation Hub Network here.
- Phase
- Not applicable
- Length of participation
- 12 months (6 months of active sampling, and date review at 12 months)
- Recruitment target
- 365
- CF sponsor
- University of Manchester
- CF sponsor type
- Academic
Who can take part?
- Age range
- 16 years and older
- Including people
- Confirmed diagnosis of cystic fibrosis (CF)
- Has had at least 1 previous exacerbation of CF lung disease, treated with oral or intravenous antibiotics, in the previous 12 months
- Has a home spirometry device and able to use this
- Excluding people
- Unable to produce sputum, spontaneous or induced, at visit
- If the potential participant is normally able to produce sputum and still wishes to take part, visit 1 can be repeated on up to two additional occasions if this is needed to obtain sputum sample.
- Infection with Mycobacteria tuberculosis
- Unable to produce sputum, spontaneous or induced, at visit