Although cystic fibrosis (CF) isn’t just a ‘lung disease’ – as it affects many parts of the body – it’s important to be aware of the effects CF does have on the lungs.
Join Team CF Trust today for the London to Brighton Cycle Ride, a mass-participation event covering 54 miles from Clapham Common in London to Madeira Drive in Brighton.
The sweat test is used as a means to establish, or exclude, a diagnosis of cystic fibrosis. Find out why it’s used for diagnosis, what the test involves and more.
Cystic fibrosis (CF) is a lifelong disease resulting from changes (mutations) in the code for one gene called the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Changes in this gene can affect the amount of protein made from this gene, or how well the protein works. When there is not enough protein or it does not work properly, some fluids in the body become sticky and cause problems in the lungs and other organs. This study will look at how well the medicine ‘VX-121’ works, in combination with other medicines. Early studies have suggested that taking these medicines may improve...
ALX-009 is composed of hypothiocyanite ion (OSCN-) and lactoferrin, two substances that are naturally occurring components of the immune system in the lungs but are lacking in CF patients’ lungs. It has been demonstrated in vitro that OSCN- and lactoferrin are capable of killing all tested Gram(-) bacteria, including bad bugs resistant to available antibiotics. This clinical trial is split into four parts. People with CF or bronchiectasis are planned to be enrolled in the fourth part, the main purpose of which is to assess the safety of ALX-009 after repeated administration of increasing doses. The doses will be chosen...
