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New report aims to reduce impact of medicine supply risks

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Last week, the Association of the British Pharmaceutical Industry (ABPI) published a new report about medicine shortages in the UK. The report explains why shortages happen, how supply chains can be made stronger, and how patients can be better protected.

A man running in the London marathon, wearing a yellow Cystic Fibrosis Trust vest

2027 TCS London Marathon

Event Date: 25/04/2027
Join Team CF for the 2027 TCS London Marathon and help us unite for a life unlimited!

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Search result from the Trials Tracker

FORMaT: A trial investigating the best treatment for Mycobacterium abscessus infections

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The aim of this study is to find the safest and most effective treatments for Mycobacterium abscessus (also called M. abscessus) infection in people with CF and non-CF bronchiectasis. There are two groups in this study: an observation group and a treatment group. The observation group will consist of people who either: have only had an M. abscessus infection once or do not currently have signs of M. abscessus infection and are not currently on a treatment for M. abscessus infection. The treatment group will consist of people who have a confirmed M. abscessus infection. Participants in the observation group...

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Trials Tracker ID
TT014236
Age range
Any age
Length of participation
3 years
Trial status
Open to recruitment
Therapeutic approach
Anti-Infective
Search result from the Trials Tracker

A dose finding study of OligoG in patients with Cystic Fibrosis

OligoG is a small sugar molecule that comes from seaweed, harvested off the coast of Norway. Studies indicate that OligoG may make CF mucus less sticky, and it may also help antibiotics to combat infections. Although OligoG has been tested and found to be safe in about 130 CF patients, more research is needed to find the best dose and to study the effect of longer term use. OligoG is given as a dry powder for inhalation. Ten capsules are to be taken twice daily. During this study patients may take their other usual medications in addition to OligoG. Part...

Results were published in 2020. The results didn’t show any true (statistically significant) improvements in lung function compared to the placebo. However, it did show that repeated inhalation of OligoG was generally safe in adults with CF. While there wasn’t a clear improvement in lung function, a detailed analysis of the methodology and results after the study finished suggests that more research into OligoG is needed to find out whether it could be a useful treatment for people with CF.  

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Trials Tracker ID
TT001881
Age range
12 years and older
Trial status
Closed with results
Therapeutic approach
Anti-Infective
Search result from the Trials Tracker

AZTEC-CF

This study aims to investigate whether it is safe and effective to use one inhaled antibiotic and one via a drip, instead of the current standard of practice of two antibiotics via a drip. Participants will receive the two different treatments the next two occasions they need to be admitted to Liverpool Heart & Chest Hospital with a chest infection. On one admission they will receive two IV antibiotics, on the other admission they will receive one IV antibiotic and inhaled aztreonam (known as Cayston®). The order they receive each treatment will be picked at random. Participants will have measurements...

Those receiving AZLI showed improved lung function and quality of life compared to those receiving current standard treatment of two IV antibiotics. While this was a small study, it suggests that larger studies are needed to confirm this as a more effective treatment for people experiencing lung exacerbations.

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Trials Tracker ID
TT001726
Age range
18 years and older
Length of participation
2 exacerbations
Trial status
Closed with results
Therapeutic approach
Anti-Infective

Quality Improvement

Cystic Fibrosis Trust’s Quality Improvement Team works to improve quality of care in CF centres across the UK.
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Edinburgh Marathon Festival 2027

Event Date: 23/05/2026


Join Team Cystic Fibrosis Trust at the Edinburgh Marathon Festival, Scotland’s biggest running weekend and one of the fastest, flattest courses in the UK.

With a distance for every age and ability, whether you’re taking on the full marathon, half, 10K, 5K or relay, you’ll be running through iconic city streets and along the stunning East Lothian coastline — all while helping to transform the future for people with cystic fibrosis.

You’ll receive dedicated support from our events team, a Cystic Fibrosis Trust running top, and fundraising guidance to help you smash your target from start line to finish.