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Bowel cancer and cystic fibrosis

There is some research to suggest that there may be an increased risk of bowel (or colorectal) cancer in people with cystic fibrosis (CF). However, this research is not conclusive. Read more about what bowel cancer is, the potential risks for people with CF and what screening involves.

What is bowel cancer?

Bowel cancer, also called colorectal cancer, affects the large bowel, which is made up of the colon and rectum.

In people who don’t have CF in the UK, bowel cancer is the fourth most common cancer. Most people diagnosed with bowel cancer are over 50 and over half are over 70.

In England, Wales and Northern Ireland, people over the age of 60 are invited to take part in bowel cancer screening. In Scotland, people are invited to take part in screening from the age of 50.

To find out more about bowel cancer, visit Bowel Cancer UK’s website.

If you are worried about your health, or experiencing any unusual bowel habits, always speak to your CF team.

What is the risk of developing bowel cancer in people with cystic fibrosis?

There is some research to suggest that people with CF may be more at risk of developing bowel cancer. However, this research is limited, and the same results have not been seen in all studies.

It is not known why people with CF might have an increased risk of developing bowel cancer. The Cystic Fibrosis Trust will be funding a Strategic Research Centre to investigate whether there is an increased risk in people with CF and why this might be, so that CF teams can understand how best to treat their patients.

How are people with CF screened for bowel cancer?

Some CF centres offer screening for bowel cancer from the age of 30 to people who want it. Screening can be performed through two different tests:

  • Faecal immunochemical test (FIT) – This test is performed at home and is done by taking a small poo sample.
  • Colonoscopy – For this test, a tube is inserted through your back passage. It has a light and a tiny camera on it that allows the person doing the exam to see your bowel lining. During a colonoscopy, small cells called polyps might be removed at the same time. These are not dangerous, but can very rarely become cancerous which is why they are always removed.

There are some small risks associated with a colonoscopy, which will be explained to you if you are offered one.

If you have any questions about bowel cancer and cystic fibrosis, please speak to your CF team, or contact our Helpline.

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