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Rest and Relax grants

Apply for Rest and Relax holiday grants from Cystic Fibrosis Trust. Financial help for people with CF to book short breaks during difficult times.

Answering questions about lung inflammation in CF to design future treatments

Lung inflammation remains a major concern for everyone with CF. However, we need better and more specific anti-inflammatory treatments. Led by Professor Robert Gray at the University of Glasgow, researchers within the DEFINE-CF SRC programme will apply cutting-edge new techniques, alongside existing methods of analysis to find and test possible new ways to treat inflammatio

Goodchild Strategic Research Centre: CFTR Folding and Function

The aim of this Strategic Research Centre (SRC) is to design new and innovative medicines to act on the CFTR protein that will be bigger difference for more people with cystic fibrosis (CF).

Strategic Research Centre: Therapeutic gene editing

Gene editing has the potential to offer a treatment for CF in the future. This research will investigate a number of laboratory-based approaches towards this goal.

ADVANCE -CFTR Development Award

Professor Nick Simmonds at the Royal Brompton Hospital is leading a research project on difficult to diagnose cystic fibrosis (CF). The title of his programme of research is Advanced Diagnostic Validation and Novel Clinical Evaluation across the CFTR spectrum, or ADVANCE-CFTR for short.

Karen Menzies PTSuppress SRC – Novel lead compounds as potential suppressor drugs for CFTR Premature Termination Codon (PTC) variants

Led by Dr Mike Gray at Newcastle University, researchers from across Europe are designing chemicals in the lab that could be used as CF medicines in the future, for those with a specific type of ‘Class 1’ mutation, known as a premature termination codon or PTCs.

Restoring the Fizz Strategic Research Centre: Pharmacological repair of bicarbonate transport in cystic fibrosis

This Trust-funded Strategic Research Centre (SRC) programme will be run by Dr Paola Vergani at University College London, and aims to better understand the flow of bicarbonate in different organs affected by CF. Researchers involved hope their studies could inform future treatment choices and help us understand more about CF disease outside of the lungs.

How does the natural chemical succinate affect lung health in people with CF

A Development Award exploring a novel role for succinate chemosensing in the pathogenesis of CF airway disease.

“This challenge is for those people who may be feeling the same despair and hopelessness that I felt”

In September, our Trustee Michelle Shore, who has cystic fibrosis (CF), will be taking on an epic challenge, walking the English coastline from Filey to Robin Hoods Bay to raise vital funds for Cystic Fibrosis Trust. We caught up with Michelle to hear more about her CF story and the inspiration behind her fundraising challenge.